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 Head Coach Simon Middleton said: "With 994 international caps between them, this is a strong England squad with a wealth of experience.
"Preparation has been good, having had 10 days training as a group already. We feel ready to take on France, a side we know well. The Six Nations is an exciting and competitive tournament and we look forward to getting the campaign underway in front of a home crowd at Twickenham.”
The two sides have faced each other twice since last year's Six Nations, which was won by France following a championship decider between the two sides in Vannes. A last-gasp try in the Women's Rugby Super Series allowed England to exact revenge on their Six Nations loss in Salt Lake City last summer, running out 17-13 winners before following up with a 10-5 victory at the Twickenham Stoop in the opening game of the Old Mutual Wealth Series in November.
Entrance to England Women v France at Twickenham on Saturday is free following the conclusion of the men's game.
England match-day 23 against France
15 Danielle Waterman (Bristol, 64 caps) 14 Lydia Thompson (Worcester Valkyries, 27 caps) 13 Emily Scarratt (Lichfield, 61 caps) 12 Amber Reed (Bristol, 32 caps) 11 Amy Wilson Hardy (Bristol, 3 caps) 10 Katy Mclean (Darlington Mowden Park Sharks, 80 caps) 9 Natasha Hunt (Lichfield, 33 caps)
1 Rochelle Clark (Worcester Valkyries, 117 caps) 2 Amy Cokayne (Lichfield, 20 caps) 3 Laura Keates (Worcester Valkyries, 56 caps) 4 Tamara Taylor (Darlington Mowden Park Sharks, 98 caps) 5 Harriet Millar-Mills (Lichfield, 38 caps) 6 Izzy Noel-Smith (Bristol, 24 caps) 7 Marlie Packer (Bristol, 40 caps) 8 Sarah Hunter (Bristol, 85 caps) (c)
16 Vicky Fleetwood (Saracens, 54 caps) 17 Justine Lucas (Lichfield, 14 caps) 18 Sarah Bern (Bristol, 4 caps) 19 Zoe Aldcroft (Darlington Mowden Park Sharks, 2 caps) 20 Poppy Cleall (Bristol, 7 caps) 21 La Toya Mason (Darlington Mowden Park Sharks, 59 caps) 22 Emily Scott (Saracens, 16 caps) 23 Rachael Burford (Aylesford Bulls, 60 caps)
England Women Six Nations fixtures
England v France Saturday 4 February, KO 7.35pm, live on Sky Sports Mix Twickenham stadium Free entry after the men's game
Wales v England Saturday 11 February, KO 11.30am, live on Sky Sports 3 Cardiff Arms Park
England v Italy Saturday 25 February, KO 1pm, live on Sky Sports 2 Twickenham Stoop
England v Scotland Saturday 11 March, KO 1pm, coverage delayed until 8pm on Sky Sports 2 Twickenham Stoop
Ireland v England Friday 17 March, KO 8pm, live on Sky Sports Mix Donnybrook Stadium, Dublin
N.B. Channel information subject to change
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